Methotrexate was actually developed in the 1940s as a cancer treatment, but years later it showed promise as an RA treatment. Today, it’s the foundational therapy in RA, and it’s often the first drug patients are prescribed after they are diagnosed. As many as 90% of all RA patients will take methotrexate at some point. Interestingly enough, it is still used to treat many forms of cancer, but at much higher doses than what is prescribed for RA.
The combination of effectiveness and safety profile makes methotrexate a therapy many patients can stay on for years.
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